Transferrin Receptor Complex, human, antibody

Product Information
Transferrin Receptor Complex, human, antibody.  

Description: Transferrin Receptor Complex, human, antibody.  

MoAb Isotype: IgG1 for all MAbs  

Clones Offered: 2A2, 1C10, 8B9, 11D3, 12A6 Hybridoma clones for MAbs 2A2 and 1C10 have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of a Balb/c mice immunized with purified transferrin from pooled human plasma. Hybridoma clones for MAbs 8B9, 11D3 and 12A6 have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with placental transferrin receptor or transferrin.  

Specificity: Human transferrin complex between transferrin and soluble transferrin receptor. MAb 2A2 reacts with N-terminal domain of human transferrin with Kd=2.85 x 10-11 M. MAbs 2A2 and 1C10 do not cross-react with mouse, rabbit, bovine transferrin and with human lactoferrin.  

Applications: Detection of transferrin in serum by sandwich immunoassay. Detection of transferrin - transferrin receptor complex by sandwich ELISA. All MAbs are working in ELISA. Recommended pairs for transferrin detection by sandwich immunoassay (coating - conjugate): 8B9 - 11D3, 8B9 - 12A6 Recommended MAbs for transferrin-transferrin receptor complex detection by ELISA sandwich method using anti-transferrin receptor MAb 23D10 (cat.No # 4Tr26) as coating: 23D10 - 8B9, 23D10 - 11D3 At 10-6 M MAbs 2A2 and 1C10 inhibit proliferation of Con-A stimulated peripheral blood lymphocytes. MAb 2A2 is working in indirect immunofluorescence on fixed, paraffin embedded human brain tissue.  

Purity: Chromatography on protein A Sepharose for MAbs 8B9, 11D3 and 12A6, and chromatography on protein G Sepharose for MAbs 2A2 and 1C10  

Presentation: PBS, pH 7.4, 0.1 % sodium azide (NaN3)  

Shipping Conditions: + 4 °C  

Comments: This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Price: $242.00

• Tell a Friend