D-Dimer, Human, Antibody

Product Information
D-Dimer, Human, Antibody.  

Description: D-Dimer, Human, Antibody.  

MoAb Isotype: IgG2a for MAbs DD1, DD6, DD10, DD22, DD41, and DD46 IgG2b for MAbs DD2, DD3, DD4, DD5, DD9, and DD44  

Clones Offered: DD1, DD2, DD3, DD4, DD5, DD6, DD9, DD10 New MAbs: DD22, DD41, DD44, DD46 Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with homogenized fibrin clot, D-dimer or high molecular weight fibrin degradation products.  

Specificity: All MAbs recognized D-dimer and high molecular weight fibrin degradation products with different specificities. See printable version for further information.  

Applications: D-dimer and high molecular weight fibrin degradation products immunoassay. All antibodies recognize D-dimer in ELISA and Western blotting under non-reducing conditions. MAbs DD22, DD41, DD44, DD46 interact with ß-chain of D-dimer in Western blotting under reducing conditions. Recommended pairs to be used in a one-step sandwich immunoassay for D-dimer detection in human plasma (coating - conjugate): DD2 - DD41 and DD2 - DD44. Recommended pairs to be used in two-step sandwich immunoassay for D-dimer detection in human plasma (coating - detection)*: DD1 - DD6, DD1 - DD4, DD1 - DD5, DD3 - DD4, DD3 - DD6, DD2 - DD6, DD2 - DD4 and DD2 - DD5 *To be analyzed in a two-step sandwich immunoassay, plasma must be diluted with 10 mM Tris-HCl buffer, pH 7.5, containing 1 M NaCl and 0.1 % Tween 20. To avoid non-specific binding the final NaCl concentration in plasma samples must be 0.5 M or more.  

Purity: Chromatography on protein A Sepharose  

Presentation: PBS, pH 7.4, 0.1 % sodium azide (NaN3)  

Shipping Conditions: + 4 °C  

Comments: This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Price: $278.00

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