BNP and NT-proBNP: established diagnostic and prognostic biomarkers of heart failure.

20 Mar, 2018


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Heart failure is a severe health problem that is characterized by an increasing prevalence and economic cost. According to the American Heart Association, in the United States nearly one million new cases are reported each year.

BNP and NT-proBNP are established diagnostic and prognostic biomarkers of heart failure. The clinical values of these markers are similar and both of them are used in clinical practice. Clinical guidelines recommend measuring either BNP or NT-proBNP in order to rule out heart failure in the initial assessment of a patient with suspected acute heart failure. Both markers can also be used to monitor the progression of the disease.


At Advanced ImmunoChemical, Inc., we provide a broad range of well-characterized monoclonal antibodies that allow for the development of sensitive and reliable immunoassays for the detection of proBNP, NT-proBNP and BNP in clinical samples. We also provide different recombinant antigens that can be used as standards and calibrators in immunoassays (see below).

For more information about the products and development of prototype immunoassays for BNP (conventional and SES-BNP™ assays) and NT-proBNP as well as of immunoassays detecting only full-length proBNP, please see our Human proBNP, BNP and NT-proBNP. Open AssayNotes.

Details and Ordering Information: monoclonal antibodies

Monoclonal Mouse Anti-Brain Natriuretic Peptide, human, in vitro

Monoclonal Mouse Anti-Brain Natriuretic Peptide, human

Monoclonal Mouse Anti-NT-proBNP, human

Monoclonal Mouse Anti-Inmune Complex 24C5-BNP proBNP, in vitro

Monoclonal Mouse Anti-Immune Complex 24C5-BNP

Details and Ordering Information: recombinant antigens, standards, plasma

Human NT proBNP, precursor, recombinant

Human pro-Brain Natriuretic Peptide, recombinant

Human proBNP, glycosylated, recombinant

Cat# 8BFP: BNP and NT-proBNP Free Plasma

BNP and NT-proBNP-free Plasma, EDTA


Our manufacturer’s scientists have been studying proBNP and its derivatives for several years and published several articles in peer reviewed journals. Product Articles

Kindly visit us at to see our other clinical diagnostic areas of interest.

Best regards,

Anne Tolles, M.Sc., President

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