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New. Biomarkers to screen for mysterious heart damage and other health issues befalling some COVID-19 patients. Testing for SARS-CoV-2 is not the only requirement in regards to managing COVID-19. Screening and monitoring for the various health issues that may arise as part of COVID-19 disease management are also needed. You can find the following biomarkers in … Read more →

Monoclonal Antibodies for Development of COVID-19 Serology Assays  To detect and measure the levels of SARS-CoV-2 antibodies as a result of exposure to COVID-19 will provide valuable information on the development of individual immunity. COVID-19 specific IgM antibodies can be detected after 3-5 days from onset of the disease. IgG antibodies appear later, however, their … Read more →

Canine C-reactive protein (cCRP) is a major acute phase protein in dogs. Its concentration increases rapidly and significantly during systemic inflammation and subsequently decreases quickly following the elimination of the source of inflammation. Several studies support the view that cCRP is a valuable diagnostic marker for the detection of the acute phase response in dogs. Its … Read more →

New D-dimer monoclonal antibodies (DD189 and DD255) allow for development of an improved immunoassay to detect D-dimer. Elevated levels of D-dimer are found in the blood of patients with pulmonary embolism, deep vein thrombosis and atherosclerosis. D-dimer diagnostic tests are widely used to exclude the diagnosis of deep vein thrombosis. In addition, increased amount of D-dimer … Read more →

Open full PDF Procalcitonin AssayNotes Procalcitonin (PCT) is a small protein (~13 kDa) that is synthesized by the C-cells of the thyroid glands. It is considered to be the main marker of disorders that are accompanied by systemic inflammation and sepsis. PCT is encoded by the CALC-1 gene and it is the precursor of the … Read more →

Tumor biomarkers play a crucial role in monitoring of response to therapy and in post-treatment surveillance of various gastrointestinal and gynecological malignancies. While the clinical value of FDA-approved tumor markers such as CEA, CA19-9 and CA125 has been established, adequate data to support FDA approval of CA72-4 as a potential biomarker are lacking and its … Read more →

Coming soon: Anti-Müllerian Hormone MAbs and Recombinant Protein. Anti-Müllerian hormone (AMH) is increasingly utilized as a biomarker of women’s reproductive health. AMH levels correlate to the size of the follicle pool. In addition, it can be used to assess the response of in vitro fertility treatment. Anti-Mullerian Hormone (AMH) is expressed by granulosa cells. Production declines when follicles … Read more →

Open full PDF High-sensitivity CRP AssayNotes. C-reactive protein (CRP) was originally discovered by Tillett and Francis in 1930 as a substance in the serum of patients with acute inflammation that reacted with the C polysaccharide of pneumococcus. CRP is a 224 residue protein with a monomer molecular mass about 25 kDa and pI 6.4. Monomers are … Read more →

Open PDF Human Papillomavirus (HPV) AssayNotes Human papillomavirus (HPV) belongs to Papillomaviruses, a diverse group of DNA-based viruses that infect the skin and mucous membranes of humans and a variety of animals. Over 100 different human papillomavirus (HPV) types have been identified on the basis of difference in the virus genome nucleotide sequences (e.g. type … Read more →

Properties Description: SmarTaq DNA Polymerase is complex mixture of a thermostable 94 kDa BioTaq DNA Polymerase purified from E. coli PVG-AI recombinant strain expressing Thermus aquaticus polymerase gene and specific monoclonal antibodies. SmarTaq from Advanced ImmunoChemical, Inc. is inactive under conditions of amplification reaction preparation. It provides improved specificity when compared to standard DNA polymerases. SmarTaq can eliminate amplification artifacts such … Read more →