Category: Article

New! Human recombinant SAA1 and SAA2: major acute phase proteins of inflammation.

22 Mar, 2018

Author:

no comments

New! Human recombinant SAA1 and SAA2: major acute phase proteins of inflammation.

Serum amyloid A (SAA) is often used as a non-specific marker of inflammation. Its concentration in blood increases in response to inflammatory stimulus such as tissue injury, infection or trauma. SAA proteins are encoded by four different genes, SAA1-SAA4. In human beings, SAA1 and SAA2 belong to the group of major acute phase proteins similarly to … Read more

BNP and NT-proBNP: established diagnostic and prognostic biomarkers of heart failure.

20 Mar, 2018

Author:

no comments

BNP and NT-proBNP: established diagnostic and prognostic biomarkers of heart failure.

Heart failure is a severe health problem that is characterized by an increasing prevalence and economic cost. According to the American Heart Association, in the United States nearly one million new cases are reported each year. BNP and NT-proBNP are established diagnostic and prognostic biomarkers of heart failure. The clinical values of these markers are similar and … Read more

Biomarkers of Myocardial Infarction: 18 antibodies and antigens for diagnosis and prognosis.

6 Mar, 2018

Author:

no comments

Biomarkers of Myocardial Infarction: 18 antibodies and antigens for diagnosis and prognosis.

Cardiovascular diseases are a group of disorders that occur in the heart and blood vessels and are the world’s leading cause of death. Researchers are currently studying whether tests that detect levels of cardiac troponin I (cTnI) in the blood my help physicians diagnose heart attacks sooner. For over 20 years, Advanced ImmuunoChemical, Inc. has been at … Read more

BNP: established cardiac biomarker for identification and severity of heart failure, as well as prognosis/monitoring.

6 Feb, 2018

Author:

no comments

BNP: established cardiac biomarker for identification and severity of heart failure, as well as prognosis/monitoring.

New. Anti-BNP Antibodies Advanced ImmunoChemical announces three new monoclonal antibodies specific to BNP. BNP is an established cardiac biomarker and used as a diagnostic and prognostic marker of heart failure. We now provide eight MAbs specific to BNP as shown in Figure 1. Figure 1. New MAbs, 100cc, 130cc and 429cc for use in combination … Read more

HbA1c – The glycated isoform of hemoglobin for the detection of hyperglycemia and type 2 diabetes.

30 Jan, 2018

Author:

no comments

HbA1c – The glycated isoform of hemoglobin for the detection of hyperglycemia and type 2 diabetes.

Click here to download full article: HbA1c- the Glycated Isoform of Hemoglobin AssayNotes Diabetes is one of the most challenging health problems in the 21st century and it is among leading causes of death in most developed economies but alarmingly also in developing economies. Diabetes causes substantial health costs because of complications often associated with … Read more

Retinol-binding protein 4 (RBP4): monoclonal antibodies not susceptible to modifications in heterogeneous RBP4 serum in detection of type 2 diabetes.

17 Jan, 2018

Author:

no comments

Retinol-binding protein 4 (RBP4): monoclonal antibodies not susceptible to modifications in heterogeneous RBP4 serum in detection of type 2 diabetes.

Retinol-binding protein (RBP4) TechNotes Open full PDF AssayNotes for RBP4. New. Advanced ImmunoChemical offers a set of mouse monoclonal anti-human RBP4 antibodies suitable for development of sandwich immunoassays for quantitative detection of circulating RBP4 in human plasma as well as for immunodetection of RBP4 in: direct ELISA, Western blotting, or to for immunoprecipitation of the antigen. … Read more

New! Recombinant Canine Parvovirus VP2 Protein

9 Jan, 2018

Author:

no comments

New! Recombinant Canine Parvovirus VP2 Protein

Canine parvovirus, type 2 (CPV-2) causes a severe and highly contagious disease in dogs. A common manifestation of parvovirus infection is hemorrhagic enteritis. The disease can be prevented by vaccination and the CPV-2 vaccine is recommended as a core vaccine that should be given to all dogs. Advanced ImmunoChemical now offers recombinant CPV-2 capsid protein … Read more

Adiponectin: predictive biomarker for glycemic efficacy in management of diabetes and metabolic syndrome.

2 Jan, 2018

Author:

no comments

Adiponectin: predictive biomarker for glycemic efficacy in management of diabetes and metabolic syndrome.

New! Advanced ImmunoChemical, Inc. now offers Adiponectin antibodies with properties that detect LMW, HMW or total Adiponectin for assay development and research (1). In addition, we also provide purified native Adiponectin that can be used as a calibrator for Adiponectin immunoassays. As obesity and metabolic syndrome have become global health burdens, there is an increasing need to … Read more

Human proBNP, BNP and NT-proBNP: diagnostic and prognostic biomarker of heart failure.

28 Nov, 2017

Author:

no comments

Human proBNP, BNP and NT-proBNP: diagnostic and prognostic biomarker of heart failure.

Brain natriuretic peptide (BNP) and the N-terminal part of the BNP precursor proBNP (NT-proBNP) are established diagnostic and prognostic biomarkers of heart failure (HF). HF is a severe clinical and public health problem that is characterized by an increasing prevalence and economic cost. Chronic heart disease, hypertension and diabetes are among the known risk factors … Read more

High Sensitivity Human C-reactive Protein: strong serum inflammatory marker and predictor of cardiovascular events without known cardiac disease.

10 Oct, 2017

Author:

no comments

High Sensitivity Human C-reactive Protein: strong serum inflammatory marker and predictor of cardiovascular events without known cardiac disease.

CRP is a 224 a.a.r. protein with molecular mass of approximately 25 kDa and a pI = 6.4 for each monomer (1). Native pentameric protein is predominantly found in plasma as a calcium dependent ligand bound by radial symmetry of five monomers forming a ring around a central core (2). High-sensitivity C-reactive protein (hsCRP) is … Read more

Chimeric Cardiac Troponin I Antibodies: early biomarker of AMI without heterophile antibody effect.

6 Sep, 2017

Author:

no comments

Chimeric Cardiac Troponin I Antibodies: early biomarker of AMI without heterophile antibody effect.

Heterophile antibodies arise when people are exposed to different animals or products derived from animals. These antibodies are typically human anti-mouse (HAMA), anti-rabbit, anti-goat, anti-sheep, anti-cow, anti-pig, anti-rat or anti-horse. As far as immunodiagnostics is concerned, the problem is most commonly associated with HAMA due to the fact that most diagnostics assays use mouse derived … Read more

Kidney Injury Molecule-1 (KIM-1): early diagnostic urinary marker

7 Jun, 2017

Author:

no comments

Kidney Injury Molecule-1 (KIM-1): early diagnostic urinary marker

It is well known that kidney injuries can tend to accom­pany many severe illness­es such as cardiac diseas­es, trauma and sepsis, and is an increasingly common and devastating compli­cation in hospitalized pa­tients. Despite improve­ments in health outcomes in many areas during recent years, mortality and morbidity rates asso­ciated with acute kidney injury (AKI) remain very … Read more

Canine C-reactive Protein (cCRP): biomarker for systemic inflammation and tissue damage, particularly in neoplastic and immune-mediated diseases.

10 May, 2017

Author:

no comments

Canine C-reactive Protein (cCRP): biomarker for systemic inflammation and tissue damage, particularly in neoplastic and immune-mediated diseases.

Acute phase proteins (APPs) constitute a group of proteins whose blood concentration changes rapidly in response to stressors such as infection and tissue damage. C-reactive protein (CRP) is a representative APP with synthesis in hepatocytes greatly increasing during systemic inflammation and in various disorders including viral and bacterial infections, sepsis and surgical trauma (1-3). Advanced … Read more

Heart-type fatty acid binding protein (H-FABP): early marker of acute cardiac syndrome and risk stratification in pulmonary embolism.

1 May, 2017

Author:

no comments

Heart-type fatty acid binding protein (H-FABP): early marker of acute cardiac syndrome and risk stratification in pulmonary embolism.

Heart-type fatty acid binding protein (H-FABP) is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation (1). Click here to view H-FABP AssayNotes and product information. Diagnostic potential: H-FABP … Read more

Biomarkers for R&D of type 2 diabetes and cardiovascular diseases: adiponectin et. al.

24 Apr, 2017

Author:

no comments

Biomarkers for R&D of type 2 diabetes and cardiovascular diseases: adiponectin et. al.

Adiponectin is an abundant hormone secreted by adipocytes. It appears to have many functions in organisms, however, the main function of adiponectin is most likely the regulation of glucose metabolism. Adiponectin is an insulin-sensitizing hormone that has been extensively studied as a prognostic and diagnostic marker of diabetes and cardiovascular diseases. Low blood adiponectin levels … Read more

Detecting pathogens and toxins transmitted to humans and vertebrates via contaminated food and water: Caliciviridae (norovirus) et al.

6 Apr, 2017

Author:

no comments

Detecting pathogens and toxins transmitted to humans and vertebrates via contaminated food and water: Caliciviridae (norovirus) et al.

Advanced ImmunoChemical, Inc. offers 5 different high quality monoclonal antibodies (MAbs) for the detection of caliciviruses. The antibodies were developed using feline calicivirus (FCV) and rabbit hemorrhagic disease virus (RHDV) as immunogens in order to obtain antibodies that would detect the most common epitopes of different caliciviruses. All MAbs detect human norovirus, feline calicivirus and … Read more

5-minute GAPDH immunodetection for Western blotting and protein normalization from Advanced ImmunoChemical.

25 Mar, 2017

Author:

no comments

5-minute GAPDH immunodetection for Western blotting and protein normalization from Advanced ImmunoChemical.

Here we announce a direct MAb 6C5-HRP conjugate in place of secondary antibodies plus a GAPDH loading control for Western blots and protein normalization available online. Click here: GAPDH Western blot Set. GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is one of the key enzymes involved in glycolysis, catalyzing the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate. Besides functioning as a … Read more

Myeloperoxidase (MPO): inflammation marker that can serve as cardiac marker.

16 Feb, 2017

Author:

no comments

Myeloperoxidase (MPO): inflammation marker that can serve as cardiac marker.

Here at Advanced ImmunoChemical, Inc., we announce a new generation of anti-MPO monoclonal antibodies suitable for the development of quantitative MPO immunoassay. Sandwich immunoassays utilizing these antibodies demonstrated exceptionable results in precise MPO immunodetection in patient’s blood samples as shown in our AssayNotes: Click here for Myeloperoxidase AssayNotes and product information. MPO causes oxidative modification … Read more

Skip to toolbar