Monoclonal mouse anti-cardiac troponin I (cTnI), in vitro

Catalog Number: 2-TIc-iv

From: $254.00

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General Category:

    Monoclonal antibodies » Cardiac Markers » Troponin I and Troponin complex

Disease Category:

    Cardiac Markers » Monoclonal antibodies » Troponin I and Troponin complex
MAbs:
4C2cc, M155cc, 19C7cc, 16A12cc, 16A11cc, MF4cc H
Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cellsof Balb/c mice immunized with free human cTnI, native human cTn complex, or human cTnI peptides.
Specificity:
Epitope specificity: None of the MAbs has cross-reaction with skeletal muscle TnI.
MAb Epitope (a.a.r.):
4C2cc 23 – 29
M155cc 26 – 35
19C7cc 41 – 49
16A12cc 86 – 90
16A11cc 86 – 90
MF4cc 190 – 196
MAb isotypes:
IgG1 for MAbs M155cc, 16A11cc, 16A12cc, MF4cc
IgG2a for MAb 4C2cc
IgG2b for MAb 19C7cc
Applications:
Fibrinogen and fibrinopeptide A immunoassay.For specific fibrinogen detection in sandwich ELISA we recommend using anti-fibrinopeptide A MAbs for coating and anti-fibrinogen MAbs for conjugation.
Recommended pairs (capture-detection):
49D2 (anti-fibrinopeptide A) – 40F11 (anti-fibrinogen)
1F7 (anti-fibrinopeptide A) – 1F3 (anti-fibrinogen)
26E7 (anti-fibrinopeptide A) – 27C8 (anti-fibrinogen)
MAbs are working also in Western blotting.
Purification:
Chromatography on protein A Sepharose
Presentation:
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
Storage Conditions:
+ 4 °C
Material safety note:
This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material.Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
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