See other Troponin T references.
See other cardiac and blood coagulation products.[/description][/add_desc]
Alternatives in vitro!
Please note that MAb 7B9 is also available as in vitro produced product under Cat.# 2-TnC-iv. For immunoassays utilizing this MAb, we recommend selecting the in vitro produced product.
[add_desc][title]Specificity:[/title][description]Human TnC. No cross-reactivity with cTnT and cTnI. All MAbs recognize TnC also in binary complex with cTnI.[/description][/add_desc]
[add_desc][title]MAb Isotypes:[/title][description]IgG1 for MAb 7B9
IgG2a for MAb 1A2
IgG2b for MAb 12G3[/description][/add_desc]
[add_desc][title]Applications:[/title][description]TnC immunoassay and immunoaffinity purification.
All MAbs work in Western blotting.
Best pair for TnC sandwich immunoassay (capture-detection): 1A2 – 7B9
MAbs can be used in high sensitivity cTnI sandwich immunoassay in pairs with antibodies specificto human cTnI ( Cat.# 2-TIc) and Tn complex ( cat #2-TC).
Best pairs for Tn complex sandwich immunoassay (capture-detection): Tcom8 ( cat #2-TC) – 7B9
[/description][/add_desc]
[add_desc][title]Purification:[/title][description]Chromatography on protein A Sepharose[/description][/add_desc]
[add_desc][title]Presentation:[/title][description] PBS, pH 7.4, 0.1 % sodium azide (NaN3)[/description][/add_desc]
[add_desc][title]Storage Conditions:[/title][description]+ 4 °C[/description][/add_desc]
[add_desc][title]Material Safety Note:[/title][description]This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material.
Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very smallappropriate care must be taken when handling this product.[/description][/add_desc]
[add_desc][title]References:[/title][description]Search Troponin C references fromPubMed.[/description][/add_desc]
[add_desc][title]References:[/title][description]Search Troponin T references from PubMed.
See all Troponin T References. See references where Monoclonal mouse anti-cardiac Troponin T (cTnT) has been used in.[/description][/add_desc]
[add_desc][title]Applications:[/title][description]Immunological and biochemical studies. Human cardiac Tn complex immunodetection in direct ELISA. MAbs can be used in high sensitivity cTnI sandwich immunoassay in pairs with antibodies specific to human cTnI (Cat.# 2-TIc) and TnC (Cat.# 2-TnC-h)
Best pairs for Tn complex immunodetection (capture-detection)Tcom8 – 7B9 Tcom8 – 7B9 (cat #2-TnC-h)19C7 (cat # 2-TIc)–20C6[/description][/add_desc]
[add_desc][title]Purification:[/title][description]Chromatography on protein A Sepharose[/description][/add_desc] [add_desc][title]Presentation:[/title][description]PBS, pH 7.4, 0.1 % sodium azide (NaN3)[/description][/add_desc] [add_desc][title]Storage Conditions:[/title][description]+ 4 °C[/description][/add_desc] [add_desc][title]Material Safety Note:[/title][description]This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material.Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.[/description][/add_desc][add_desc][title]References:[/title][description]Search Troponin reference from PubMed.[/description][/add_desc]
New. Biomarkers to screen for mysterious heart damage and other health issues befalling some COVID-19 patients. Testing for SARS-CoV-2 is not the only requirement in regards to managing COVID-19. Screening and monitoring for the various health issues that may arise as part of COVID-19 disease management are also needed. You can find the following biomarkers in … Read more
Cardiovascular diseases are a group of disorders that occur in the heart and blood vessels and are the world’s leading cause of death. Researchers are currently studying whether tests that detect levels of cardiac troponin I (cTnI) in the blood my help physicians diagnose heart attacks sooner. For over 20 years, Advanced ImmuunoChemical, Inc. has been at … Read more
Troponin B-type natriuretic peptide IGFBP-4 and PAPP-A Transferrin receptor Adiponectin D-dimer Troponin Barth JH, et al. (2014) Recommendation to harmonize the units for reporting cardiac troponin results.Clin Chim Acta. 2014 May 15(432):166. Filatov VL, et al. (1998) Epitope mapping of anti-troponin I monoclonal antibodies. Biochem. Mol. Biol. Int. 45(6), 1179-1187. Filatov VL, et al. (1999) Troponin: structure, properties, … Read more
Filatov VL, et al. (1998) Epitope mapping of anti-troponin I monoclonal antibodies. Biochem. Mol. Biol. Int. 45(6), 1179- 1187. Filatov VL, et al. (1999) Troponin: structure, properties, and mechanism of functioning. Biochemistry 64(9), 969-985. Katrukha A, et al. (1999) Biochemical factors in uencing measurement of cardiac troponin I in serum. Clin. Chem. Lab. Med. 37(11-12), … Read more
Product Patents Patents related to diagnostics of cardiovascular diseases. Immunoassay Kit for Quantification of BNP and proBNP US 9145459 The present invention relates to an immunoassay for detection of BNP, proBNP and fragments thereof. Essentially the assay comprises: a) contacting the antigen with a first antibody specific to a fragment corresponding to … Read more
We offer monoclonal antibodies and recombinant antigens for diagnostic immunoassays for several animal diseases, including cardiovascular disease, inflammation, infectious and renal diseases. CANINE NEW! Canine C-reactive Protein (cCRP), Antibodies — (Cat #2-CRP-c) & Recombinant Canine C-reactive Protein (cCRP) — (Cat #7-CRP-c) NEW! Canine Serum Amyloid A (SAA) — (Cat #2-SAA-a) & Recombinant Canine Serum Amyloid A … Read more
Advanced ImmunoChemical offers 5 monoclonal antibodies, in addition to the recombinant human and recombinant rabbit antigens, for the detection of glyceraldehyde-3-phosphate dehydrogenase, an enzyme known for its catalyzing role in glycolysis. These antibodies and antigens are sufficient for immunodetection of GAPDH by Western blotting, sandwich immunoassays, and other immunocytochemical processes. Click here to view GAPDH Product … Read more
Citations: 2010 – 2016 [HTML] from nature.com Tissue kallikrein-modified human endothelial progenitor cell implantation improves cardiac function via enhanced activation of akt and increased angiogenesis Y Yao, Z Sheng, Y Li, C Fu, G Ma, N Liu, J Chao… – Laboratory Investigation, 2013 Abstract Endothelial progenitor cells (EPCs) have been shown to enhance angiogenesis not … Read more
EZH2 inhibition blocks multiple myeloma cell growth through upregulation of epithelial tumor suppressor genes H Hernando, KA Gelato, R Lesche, G Beckmann… – Molecular cancer …, 2015 Abstract Multiple myeloma is a plasma cell malignancy characterized by marked heterogeneous genomic instability including frequent genetic alterations in epigenetic enzymes. In particular, the histone methyltransferase Enhancer of … Read more
See references where our products have been used. Click the title of the article to read the whole article in a new browser window. Cat# 1-pINS: Monoclonal mouse anti-human proinsulin Back SH, et al. (2009) Translation Attenuation through eIF2 [alpha] Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in [beta] Cells. Cell Metabolism 10(1), … Read more
Molecular Biology SmarTaq Polymerase AssayNotes Cardiac Markers Chimeric cardiac troponin I antibodies AssayNotes ProBNP and proBNP-derived peptides (BNP and NT-proBNP) AssayNotes Antibodies for New Type of BNP Immunoassay AssayNotes hsCRP AssayNotes PAPP-A AssayNotes Myoglobin AssayNotes Heart type fatty acid binding protein (H-FABP) AssayNotes Cystatin C AssayNotes Myeloperoxidase AssayNotes Lp-PLA2 AssayNote Cardiac Troponin (cTnT) AssayNotes … Read more
Troponin Gomes, A.V, Potter,J.D., Szczesna-Cordary, D. (2002) The role of Troponin in muscle contraction. Life, 54: 323-333. Marston,S.B., Redwood,C.S. (2003) Modulation of thin fi lament activation by breakdown or isoform witching of thin fi lament Proteins. Circ. Res., 93: 1170-1178. Sarko J, Pollack CV Jr. (2002) Cardiac troponins. J Emerg Med. 2002, 23(1), pp. 57-65. … Read more