Category: Assay Notes

Pair recommendations for SARS-CoV-2 antibodies in lateral flow

5 Jan, 2021

Author:

no comments

Pair recommendations for SARS-CoV-2 antibodies in lateral flow

Now available: monoclonal antibodies specific to SARS-CoV-2 nucleoprotein in lateral flow. Four anti-SARS-CoV-2 nucleoprotein antibodies are now available from Advanced ImmunoChemical in their final forms: in vivo C518, C525, C706 and C715. In addition, one of our anti-Spike clones, RBD1107, is now available as an in vitro product R107. The antibodies have been tested with COVID-19 positive patient samples. The best pairs in … Read more

Monoclonal antibodies and antigens for SARS-CoV-2 assay development.

15 Dec, 2020

Author:

no comments

Monoclonal antibodies and antigens for SARS-CoV-2 assay development.

Now available: eleven monoclonal antibodies specific to SARS-CoV-2 Nucleoprotein and three specific to Spike RBD, plus antigens. SARS-CoV-2 is a novel coronavirus causing COVID-19. In March 2020, the World Health Organization announced the COVID-19 outbreak as a pandemic. SARS-CoV-2 belongs to a large family of single-stranded RNA viruses (+ssRNA). Beta-coronaviruses such as SARS-CoVs can cross species … Read more

Now available: SARS-CoV-2 Spike RBD

17 Nov, 2020

Author:

no comments

Now available: SARS-CoV-2 Spike RBD

Now available: SARS-CoV-2 Spike RBD antigen from Advanced ImmunoChemical. Our recombinant SARS-CoV-2 Spike RBD antigen has been produced in mammalian cells Purity is over 95%. It is provided in lyophilized form and can be used in the development of COVID-19 serology (antibody) tests. SARS-CoV-2 Spike RBD is a fragment Arg319-Phe541 of the spike surface glycoprotein … Read more

Recombinant Rb Cardiac Troponin I Antibodies (cTnI): targeted to epitope region 24-40 a.a.r. of cTnI.

27 Oct, 2020

Author:

no comments

Recombinant Rb Cardiac Troponin I Antibodies (cTnI): targeted to epitope region 24-40 a.a.r. of cTnI.

New! The cardiac isoform of Troponin I (cTnI) is used as a gold standard as marker of acute myocardial infarction (AMI). The region 24-40 aar of cTnI is a perspective target for monoclonal antibodies (MAb), because it is less affected by the action of autoantibodies and is not hindered by the other components of troponin … Read more

New! GFAP Antibodies: differentiate hemorrhagic versus ischemic stroke

24 Sep, 2020

Author:

no comments

New! GFAP Antibodies: differentiate hemorrhagic versus ischemic stroke

Traumatic brain injuries (TBIs), including concussions, are one of the main public health concerns globally. TBI diagnosis is currently based on clinical assessment using scores such as Glasgow coma scale and computer tomography. However, scores can be compromised for various reasons and the computer tomography is less than perfect too as even in severe cases … Read more

New! Polyclonal Antibodies to Canine CRP: marker of systemic inflammation

4 Sep, 2020

Author:

no comments

New! Polyclonal Antibodies to Canine CRP: marker of systemic inflammation

In dogs, C-reactive protein (CRP) can be used as a marker of inflammation. Its concentration in blood increases rapidly in systemic inflammation and decreases quickly during recovery. It has been shown to increase in disorders such as bacterial infections, sepsis and pyometra, as well as in the case of post-surgical infections. The marker responds to … Read more

CT-IGFBP-4 as a Novel Prognostic Biomarker in Acute Heart Failure

21 Aug, 2020

Author:

no comments

CT-IGFBP-4 as a Novel Prognostic Biomarker in Acute Heart Failure

In a recent article, researchers at HyTest, Ltd. continued to study the prognostic value of insulin-like growth factor binding protein-4 (IGFBP-4) fragments in cardiac related diseases. The goal of the study was to assess the carboxy-terminal fragment (CT-IGFBP4) for the prognosis of outcomes of patients with acute heart failure. Read below: https://pubmed.ncbi.nlm.nih.gov/31967738/ The study showed … Read more

Beta-Amyloid 1–42 Assay Note

22 Aug, 2019

Author:

no comments

Beta-Amyloid 1–42 Assay Note

Click here to download the Beta-Amyloid 1–42 Assay Note (PDF). Alzheimer’s disease (AD) is a complex progressive neurodegenerative disease that affects approximately 14 million people in Europe and the United States, including almost one-half of the population aged 85 years and over (43%). Alzheimer’s disease is the most common cause of dementia and it is … Read more

New! Recombinant Canine Parvovirus VP2 Protein

6 Dec, 2018

Author:

no comments

New! Recombinant Canine Parvovirus VP2 Protein

Canine parvovirus, type 2 (CPV-2) causes a severe and highly contagious disease in dogs. A common manifestation of parvovirus infection is hemorrhagic enteritis. The disease can be prevented by vaccination and the CPV-2 vaccine is recommended as a core vaccine that should be given to all dogs. Advanced ImmunoChemical now offers recombinant CPV-2 capsid protein … Read more

BNP: established cardiac biomarker for identification and severity of heart failure, as well as prognosis/monitoring.

6 Feb, 2018

Author:

no comments

BNP: established cardiac biomarker for identification and severity of heart failure, as well as prognosis/monitoring.

New. Anti-BNP Antibodies Advanced ImmunoChemical announces three new monoclonal antibodies specific to BNP. BNP is an established cardiac biomarker and used as a diagnostic and prognostic marker of heart failure. We now provide eight MAbs specific to BNP as shown in Figure 1. Figure 1. New MAbs, 100cc, 130cc and 429cc for use in combination … Read more

HbA1c – The glycated isoform of hemoglobin for the detection of hyperglycemia and type 2 diabetes.

30 Jan, 2018

Author:

no comments

HbA1c – The glycated isoform of hemoglobin for the detection of hyperglycemia and type 2 diabetes.

Click here to download full article: HbA1c- the Glycated Isoform of Hemoglobin AssayNotes Diabetes is one of the most challenging health problems in the 21st century and it is among leading causes of death in most developed economies but alarmingly also in developing economies. Diabetes causes substantial health costs because of complications often associated with … Read more

Retinol-binding protein 4 (RBP4): monoclonal antibodies not susceptible to modifications in heterogeneous RBP4 serum in detection of type 2 diabetes.

17 Jan, 2018

Author:

no comments

Retinol-binding protein 4 (RBP4): monoclonal antibodies not susceptible to modifications in heterogeneous RBP4 serum in detection of type 2 diabetes.

Retinol-binding protein (RBP4) TechNotes Open full PDF AssayNotes for RBP4. New. Advanced ImmunoChemical offers a set of mouse monoclonal anti-human RBP4 antibodies suitable for development of sandwich immunoassays for quantitative detection of circulating RBP4 in human plasma as well as for immunodetection of RBP4 in: direct ELISA, Western blotting, or to for immunoprecipitation of the antigen. … Read more

New! Recombinant Canine Parvovirus VP2 Protein

9 Jan, 2018

Author:

no comments

New! Recombinant Canine Parvovirus VP2 Protein

Canine parvovirus, type 2 (CPV-2) causes a severe and highly contagious disease in dogs. A common manifestation of parvovirus infection is hemorrhagic enteritis. The disease can be prevented by vaccination and the CPV-2 vaccine is recommended as a core vaccine that should be given to all dogs. Advanced ImmunoChemical now offers recombinant CPV-2 capsid protein … Read more

Adiponectin: predictive biomarker for glycemic efficacy in management of diabetes and metabolic syndrome.

2 Jan, 2018

Author:

no comments

Adiponectin: predictive biomarker for glycemic efficacy in management of diabetes and metabolic syndrome.

New! Advanced ImmunoChemical, Inc. now offers Adiponectin antibodies with properties that detect LMW, HMW or total Adiponectin for assay development and research (1). In addition, we also provide purified native Adiponectin that can be used as a calibrator for Adiponectin immunoassays. As obesity and metabolic syndrome have become global health burdens, there is an increasing need to … Read more

Rat C-peptide and Proinsulin: diagnostic markers for diabetes and hypoglycemia

12 Dec, 2017

Author:

no comments

Rat C-peptide and Proinsulin: diagnostic markers for diabetes and hypoglycemia

Advanced ImmunoChemical offers monoclonal antibodies specific to different parts of rat C-peptides I and II. Thoroughly chosen epitopes and original approaches for selecting specific monoclonal antibodies have produced highly sensitive and specific antibodies which make C-peptide detection possible without cross-reactivity with native proinsulin or other known forms of partially processed proinsulin. Moreover we also offer … Read more

Canine thyroid stimulating hormone (TSH, thyrotropin): biomarker to reliably evaluate thyroid function

5 Dec, 2017

Author:

no comments

Canine thyroid stimulating hormone (TSH, thyrotropin): biomarker to reliably evaluate thyroid function

New Products: Canine TSH MAbs and Recombinant Antigen Hypothyroidsim is one of the most frequent canine endocrine disorders. The diagnosis of hypothyroidism is based on the presence of clinical signs, thyroid function test results and response to the thyroid hormone replacement therapy. A low circulating total T4 concentration suggests hypothyroidism. However, in order to reliably evaluate … Read more

Human proBNP, BNP and NT-proBNP: diagnostic and prognostic biomarker of heart failure.

28 Nov, 2017

Author:

no comments

Human proBNP, BNP and NT-proBNP: diagnostic and prognostic biomarker of heart failure.

Brain natriuretic peptide (BNP) and the N-terminal part of the BNP precursor proBNP (NT-proBNP) are established diagnostic and prognostic biomarkers of heart failure (HF). HF is a severe clinical and public health problem that is characterized by an increasing prevalence and economic cost. Chronic heart disease, hypertension and diabetes are among the known risk factors … Read more

Skip to toolbar